Ciprofloxacin Hydrochloride
Ciprofloxacin Hydrochloride is a second-generation fluoroquinolone antibiotic. It acts by inhibiting bacterial DNA gyrase and topoisomerase IV, preventing bacterial DNA replication and transcription. It is highly active against aerobic gram-negative bacilli.
Dosage by Body Weight
The usual adult oral dosage is 250 mg to 750 mg every 12 hours, depending on the severity and nature of the infection. It should be taken with a full glass of water, and the patient should remain well-hydrated. Avoid administering with dairy products, antacids, or iron supplements as they impair absorption.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Fluoroquinolones are generally not recommended for routine pediatric use due to risks of arthropathy, unless treating complicated UTIs, pyelonephritis, or inhalation anthrax.
- Body Weight
- 5-7 kg
- Dose
- 50 mg to 100 mg
- Frequency
- Every 12 hours
- Tracking Notes
- Based on pediatric dosing guidelines of 10-20 mg/kg/dose. Use oral suspension formulation for precise dosing.
- Body Weight
- 8-10 kg
- Dose
- 80 mg to 160 mg
- Frequency
- Every 12 hours
- Tracking Notes
- Administer with caution. Monitor closely for signs of joint pain, tendon inflammation, or severe diarrhea.
- Body Weight
- 11-15 kg
- Dose
- 110 mg to 250 mg
- Frequency
- Every 12 hours
- Tracking Notes
- Avoid taking with calcium-fortified juices or antacids containing magnesium or aluminum.
- Body Weight
- 16-20 kg
- Dose
- 160 mg to 350 mg
- Frequency
- Every 12 hours
- Tracking Notes
- Ensure adequate fluid intake to prevent the development of crystalluria.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Fluoroquinolones are generally not recommended for routine pediatric use due to risks of arthropathy, unless treating complicated UTIs, pyelonephritis, or inhalation anthrax. |
| 5-7 kg | 50 mg to 100 mg | Every 12 hours | Based on pediatric dosing guidelines of 10-20 mg/kg/dose. Use oral suspension formulation for precise dosing. |
| 8-10 kg | 80 mg to 160 mg | Every 12 hours | Administer with caution. Monitor closely for signs of joint pain, tendon inflammation, or severe diarrhea. |
| 11-15 kg | 110 mg to 250 mg | Every 12 hours | Avoid taking with calcium-fortified juices or antacids containing magnesium or aluminum. |
| 16-20 kg | 160 mg to 350 mg | Every 12 hours | Ensure adequate fluid intake to prevent the development of crystalluria. |
Formulation
Purpose
Treatment of various bacterial infections including urinary tract infections (UTIs), lower respiratory tract infections, skin and skin structure infections, bone and joint infections, infectious diarrhea, typhoid fever, and uncomplicated gonorrhea.
Generic Name
CiprofloxacinBranded Drug Names
Ciprofloxacin Hydrochloride is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.